Vitamin D3

Vitamin D3

Vitamin D is a nutrient, hormone and immunomodulator.

Vitamin D (calciferol) is formed in our body (in the skin) under the influence of ultraviolet sunlight in the form of vitamin D3 (cholecalciferol). There is, in addition, a less active type of this vitamin, which is formed in human skin from plant foods rich in ergosterol – D2 (ergocalciferol). From the skin, vitamin D travels to the liver, where it is converted into a form of hormone that regulates calcium homeostasis, and then to the kidneys. This active form of vitamin D causes the formation of a specific calcium-binding protein in the intestines and kidneys, which enhances the absorption of calcium in the small intestine and at the same time accelerates its absorption in the kidneys, returning this trace element to the blood and reducing its loss in the urine.

With age, the formation of vitamin D in the human body decreases, i.e. Even if an elderly person is regularly exposed to the sun, significantly less vitamin will be formed in his skin than at an earlier age.

Vitamin D deficiency can occur due to a lack of nutrition, insufficient formation of it in the skin due to exposure to sunlight, and liver and kidney diseases. Russia and other countries in our region are located in a zone of low insolation, so almost all of their residents are at risk for vitamin D deficiency.

Vitamin D is necessary not only for regulating calcium levels in the blood and bone mineral density. It has been established that many organs and tissues of our body have vitamin D receptors, which means that vitamin D affects not only bone tissue, but also many other organs and systems. As a hormone, it is also involved in the regulation of more than 200 genes in the body and has multifunctional effects.

Chronic vitamin D deficiency is a risk factor for the development of a number of serious diseases with a long inactive period.

For the health of the musculoskeletal system: vitamin D is necessary for the regulation of calcium and phosphorus metabolism during the formation of bone tissue, teeth and for the prevention and treatment of osteoporosis.

Increases the absorption of calcium and phosphorus in the small intestine, and the reverse absorption of calcium in the kidneys.

Increases the production of parathyroid hormone (parathyroid hormone) and the activity of osteoclast cells, which regulate the flow of calcium into the blood during blood calcium deficiency.

For the health of the immune system: vitamin D supports innate and acquired immunity, affects the function of blood cells of lymphocytes and the activity of blood cells – macrophages, the production of inflammatory factors – cytokines, increases the production of interleukin-1 and prostaglandin E2. Participates in the synthesis of its own interferon.

The immunomodulatory role of vitamin D has been established; it forms antiviral and antibacterial immunity (in tuberculosis) with the production of antibodies.

Under the influence of vitamin D, blood cells are formed.

For healthy skin: Vitamin D regulates the proliferation and variety of skin cells and can be used in the treatment of psoriasis, vitiligo and cancer. Reduces the risk and manifestations of autoimmune reactions.

Endocrine system: vitamin D regulates the function of the thyroid gland, pancreas, gonads; regulates the embryonic development of the fetus, spermatogenesis and reproductive function, regulates DNA. Reduces the risk of type 1 diabetes (increases insulin secretion).

Supports the health of barrier systems: the respiratory system and intestines.

Regulates important processes of vital metabolism: ATP synthesis for energy, blood clotting, ethanol detoxification, etc.

Provides prevention of: cardiovascular diseases, the development of multiple sclerosis.

Provides prevention of tumor diseases: colon, kidneys, ovaries, mammary and prostate glands.

Children: Vitamin D deficiency is the main cause of rickets in children. Excess weight during pregnancy has been found to lead to vitamin D deficiency in mother and child throughout life.

Nervous system health: Studies have shown that a lack of vitamin D may cause memory loss, insomnia, and mood instability.

Vitamin D content in food is insufficient. With a normal diet, about 0.7-5.4 mcg of vitamin D per day enters our body with food, which is clearly not enough to maintain normal levels.

Its intake can be increased to 10 mcg by including foods rich in vitamin D in the diet (cod liver oil (250 mcg/100 g), cod liver (100 mcg/100 g), fatty herring (22.5 mcg/ 100 g), egg yolk and meat – 2.0 mcg, beef liver and butter – 1.3-1.5 mcg per 100 g of product.

Vitamin D3 is absorbed by approximately 50%. The absorption of vitamin D2 is lower, but this plant vitamin is a favorite in the diet of vegetarians. The level of vitamin D in the body can be determined by a blood test for 25-hydroxyvitamin D in accordance with the recommendations of endocrinologists.

In order to ensure optimal vitamin D levels (50-60 ng/ml), it is recommended to take at least 4000 IU (100 mcg) per day, monitoring the level of 25-hydroxyvitamin D in the blood.

The average vitamin D intake for adults should be 2,000 IU (50 mcg) per day for a normal lifestyle and 4,000 IU (100 mcg) per day for people at risk (those with chronic diseases).

In most multivitamin preparations, the vitamin D content ranges from 2.5 to 10 mcg, which does not meet the physiological requirement. Therefore, we recommend taking additional vitamin D.

Vitamin D3 NSP is obtained as a result of biotechnological synthesis from natural, environmentally friendly raw materials from Australia and New Zealand. Pharmaceutical grade mannitol, sorbitol, and xylitol from natural, non-GMO sources are added as sweeteners.